China uses modern biotechnology to produce chitosan

According to the Dalian Institute of Chemical Physics, Chinese Academy of Sciences, scientists in China have used modern biotechnology for the first time in the world and successfully developed oligosaccharides, oligopeptides and biotechnology-related products such as chitooligosaccharides. Dalian Zhonggegeike Biotechnology Co., Ltd. has established an annual output of 30 tons of chitosan oligosaccharides using the independently developed enzymatic reaction-membrane separation coupling technology, which has the potential to promote the application of chitosan in China and industrialization of sugar bioengineering products. Significance.
The technology developed by Du Fuguang, a researcher at the Dalian Institute of Chemical Physics, Chinese Academy of Sciences, has advantages over traditional methods for producing strong acids and oxidative degradation chemicals, such as controllability of polymerization, high product activity, and non-polluting production processes. This technology has obtained national patents. According to reports, the chitosan oligosaccharide produced by the enzyme reaction-membrane separation coupling technique refers to oligosaccharides in which 2 to 10 glucosamines are linked by β-1,4-glycosidic bonds. It utilizes the deacetylation treatment of the chitin in the abundance of crustaceans (shrimp, crab shells, etc.) in the ocean to obtain chitosan as raw material, and obtains the oligomeric glucosamine by means of biochemical engineering technology, ie, chitosan oligosaccharide.
Using this research achievement, researchers have also successfully developed chitosan oligosaccharide immunomodulatory “Oliqishan” capsules, “Paiqian” capsules that promote lead excretion, and it has the function of regulating blood lipids, and has protective function against chemical liver damage. "Kangkang Qishan" capsule health food has been industrialized. The new chitosan oligosaccharide feed additive (oligosaccharide-COS) has been approved by the National Feed Evaluation Committee and the product will be on the market soon.

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