Germany developed synthetic medical guide wire

Release date: 2009-04-01

Recently, the Fraunhofer Institute in Germany announced through its website that they have developed a new type of synthetic material guide wire. The results of this study can make patients with interventional therapy far from the worrying X-ray radiation problems in the treatment process, but also get rid of the contrast agent. At the JEC Composites Exhibition in Paris, the world's largest composites exhibition on March 24th, researchers showed the new guide wire.

In previous interventional procedures, such as cardiac intervention, the doctor can puncture the cannula through the superficial artery (usually the femoral artery), extend the catheter into the blood vessel, and pass through the arterial system to the heart to examine the patient's coronary artery. Whether the heart valve or myocardium has a lesion and is treated locally. The special catheter inserted into the blood vessel has a metal guide wire that can be used as a navigation aid. The doctor can control the catheter by pushing and pulling and rotating to control the guidewire. However, during the course of the treatment, the patient must be scanned with X-rays to obtain a CT image of the patient, so that the doctor can accurately see the position of the catheter in the arterial system in order to proceed to the next step. However, during CT imaging, X-rays have a large negative impact on the patient, and in order for the patient's vasculature and soft tissue to be visible in the image, a contrast agent must also be injected.

Now researchers at the Fraunhofer Institute for Product Process Research (IPT) have discovered a way to avoid X-ray radiation without having to endure contrast agents. Together with colleagues at Philips and Aachen School of Medicine, they invented a guidewire made of fiberglass reinforced synthetic material. IPT scientist Adrian Schutt said that a guide wire made of synthetic material can replace CT imaging with magnetic resonance imaging, and metal wire can not be magnetic resonance imaging. Metal guidewires become superheated during magnetic resonance, causing damage to blood vessels and protein. For doctors and patients, magnetic resonance imaging has many advantages: it does not require ionizing radiation in CT imaging, and it does not require contrast agents to see soft tissue well.

Currently, researchers are using the pultrusion method (a standard method of producing jointless guidewires from glass fiber reinforced synthetic materials) to make this two-meter-long guide wire. Xu Te explained that the new guide wire is only 0.5 mm in diameter or even smaller, which should be the smallest guide wire so far.
Shanghai Medical Device Industry Association

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