Prevention and Control of Fusarium Wilt of Medicinal Mushroom

1. Pathogens and transmission. The pathogen of Fusarium oxysporum f. sp. was F. oxysporum chrysanthemum, a subgenus fungus. It is mainly wintering in the soil with chlamydospore, or a long period of saprophytic life. The optimum temperature for the development of germs is 24-28°C, the highest 37°C, and the lowest 17°C. The disease only damages chrysanthemums. If the conditions are suitable, chrysanthemum infection can be dead in 2 weeks. Moist or waterlogged fields are prone to disease, especially after the rain water, high temperature and rain, excessive nitrogen fertilizer application, soil acidosis and other conditions are easy to disease. In the field, germs are spread mainly through irrigation water, or they can be carried away by the wind as the disease is spread.

2. Symptoms. At the time of initial onset, the leaf color became light yellow, the leaves wilted, the base of the stem was light brown, the vascular bundle at the base of the transverse stem turned brown, and the vascular bundles of the upwardly spreading shoots gradually turned pale brown, and the downward spread caused root necrosis or It turns black and rot, and some stems are cracked. When the humidity is high, it produces white mold, which is the pathogen mycelium and conidia. The disease is slow to spread, and some plants have yellowing, wilting or rot.

3. Control methods. 1 selection of species. Select suitable local disease-resistant varieties for cultivation, and select sand soil with good drainage conditions. 2 Strengthen field management. Use compost or decomposed organic fertilizer made from fermented bacteria; rationally irrigate and strengthen the management of canal and ditch, avoid as much as possible the field is wet or water after rain, and rotate with other crops. 3 drug control. Apply 50% carbendazim WP 500 times solution, 50% TCH copper wettable powder 400 times solution, or irrigate with 30% basic copper sulphate suspending agent 400 times at the beginning of the disease. Liquid 0.4 ~ 0.5L, depending on the condition of irrigation 2 to 3 times.

[Composition]

The main component of this preparation is human immunoglobulin, which is prepared by cold ethanol fractionation of human plasma from healthy donors. The manufacturing process contains a step to remove anticomplementary activity and a dual viral inactivation process. It contains a suitable amount of glucose or maltose as stabilizer (see table below), but does not contain any antiseptic or antibiotic. The distribution of IgG subclasses is close to the serum level of normal subjects and maintains the bioactivity of Fc fragment of IgG.

[Indications]

1. Primary agammaglobulinemia, such as X-linked hypogammaglobulinemia, common variant immunodeficiency diseases, immunoglobulin G subclass deficiency, etc.

2. Secondary immunoglobulin deficiency diseases, such as severe infection, septicemia of newborn, etc

3. Autoimmune diseases, such as primary thrombocytopenic purpura, Kawasaki disease

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