China Recommend Emergency Contraception Ulipristal Acetate Upa CAS 126784-99-4 Ulipristal

Model NO.: 126784-99-4
Name: Ulipristal Acetate
Alias: Ulipristal
CAS: 126784-99-4
Appearance: White Cyrstalline Powder
Express Way: EMS, FedEx, TNT, DHL, Hkems, UPS
Trademark: WHSO
Transport Package: 1kg/25kg/Package
Specification: 99%
Origin: Hongkong
HS Code: 121425246
Model NO.: 126784-99-4
Name: Ulipristal Acetate
Alias: Ulipristal
CAS: 126784-99-4
Appearance: White Cyrstalline Powder
Express Way: EMS, FedEx, TNT, DHL, Hkems, UPS
Trademark: WHSO
Transport Package: 1kg/25kg/Package
Specification: 99%
Origin: Hongkong
HS Code: 121425246
China Recommend Emergency Contraception Ulipristal Acetate UPA CAS 126784-99-4 Ulipristal


Product Name:Ulipristal Acetate
Synonyms:Ulipristal;Ulipristal acetate;Ulipristal acetate
CAS:126784-99-4
MF:C28H35NO3
MW:433.5824
EINECS:1312995-182-4
Product Categories:API;Aromatics;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals;Steroids;Final material;Inhibitors
Melting point: 183-185 ºC
Density: 1.19
Chemical Properties: White powders
Purity:99%
Package: 10g/100g/1000g/foil bag
Uses: Α selective labelled progesterone receptor modulator.
Uses: Ulipristal acetate is a selective progesterone receptor modulator.


Pharmacological action :

Ulinastal acetate is a progesterone agonist/antagonist that inhibits or delays the ovulation; however, changes in the endometrium may also be a cause of efficacy.

Ulinastal acetate belongs to the category of selective progesterone receptor modulator, and it has partial agonistic action to progesterone receptor antagonism and partial agonism. It binds to progesterone receptors in the human body and prevents progesterone receptor binding. The efficacy of Ulinastal acetate depends on the time of administration in the menstrual cycle. Administration during the mid-follicular hyperplasia would suppress follicle formation and decrease the estradiol concentrations. And the administration during the in the peak period of follicular hyperplasia can delay the breakdown of follicles from 5 to 9 days. Although early luteal phase of administration cannot significantly delay the endometrial maturation, it can reduce the thickness of the endometrium within 0.6±2.2mm(average value ±SD).


Ulipristal acetate Description

Ulipristal acetate (UPA) is a selective progesterone receptor modulator. Attributing to its higher efficacy and a similar rate of side effects compared to levonorgestrel emergency contraception, it is now recommended as first line treatment for emergency contraception. Emergency contraception is defined as the use of drug or device after unprotected or under-protected intercourse to prevent an unwanted pregnancy. Ulipristal acetate can be used up to 5 days (120 h) after unprotected sexual intercourse .

As progesterone promotes the growth of uterine fibroids, the blocking characteristic of ulipristal acetate can thereby be used to reduce the size of uterine fibroids. Ulipristal acetate has also shown efficacy with a significant reduction in uterine bleeding caused by uterine fibroids. The treatment of fibroids by ulipristal acetate should begin in the first week of a menstrual period .

Drugs or herbal products that induce enzymes, including CYP3A4, such as carbamazepine, phenytoin, rifampin, St. John's Wort, etc., may decrease the plasma concentrations of ulipristal acetate, and may decrease its effectiveness while CYP3A4 inhibitors such as itraconazole, ketoconazole, etc., may increase plasma concentrations of ulipristal acetate .

The half-life after oral intake is 32 h; it binds to plasma proteins for 97-99%, and it is metabolized by the citochrome P450 .


 
Our advantages:

1, High quality with competitive price:
1) Standard:BP/USP/EP/Enterprise standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.

2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment.Tracking number available
2) Secure and discreet shipment.Various transportation methods for your choice.
3) Customs pass rate ≥99%
4)  We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.

3,We have clients throughout the world.
 1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
3)  High quality,competitive price,fast delivery ,first-class service gain the trust and praise from the customers.
China Recommend Emergency Contraception Ulipristal Acetate UPA CAS 126784-99-4 Ulipristal


Product Name:Ulipristal Acetate
Synonyms:Ulipristal;Ulipristal acetate;Ulipristal acetate
CAS:126784-99-4
MF:C28H35NO3
MW:433.5824
EINECS:1312995-182-4
Product Categories:API;Aromatics;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals;Steroids;Final material;Inhibitors
Melting point: 183-185 ºC
Density: 1.19
Chemical Properties: White powders
Purity:99%
Package: 10g/100g/1000g/foil bag
Uses: Α selective labelled progesterone receptor modulator.
Uses: Ulipristal acetate is a selective progesterone receptor modulator.


Pharmacological action :

Ulinastal acetate is a progesterone agonist/antagonist that inhibits or delays the ovulation; however, changes in the endometrium may also be a cause of efficacy.

Ulinastal acetate belongs to the category of selective progesterone receptor modulator, and it has partial agonistic action to progesterone receptor antagonism and partial agonism. It binds to progesterone receptors in the human body and prevents progesterone receptor binding. The efficacy of Ulinastal acetate depends on the time of administration in the menstrual cycle. Administration during the mid-follicular hyperplasia would suppress follicle formation and decrease the estradiol concentrations. And the administration during the in the peak period of follicular hyperplasia can delay the breakdown of follicles from 5 to 9 days. Although early luteal phase of administration cannot significantly delay the endometrial maturation, it can reduce the thickness of the endometrium within 0.6±2.2mm(average value ±SD).


Ulipristal acetate Description

Ulipristal acetate (UPA) is a selective progesterone receptor modulator. Attributing to its higher efficacy and a similar rate of side effects compared to levonorgestrel emergency contraception, it is now recommended as first line treatment for emergency contraception. Emergency contraception is defined as the use of drug or device after unprotected or under-protected intercourse to prevent an unwanted pregnancy. Ulipristal acetate can be used up to 5 days (120 h) after unprotected sexual intercourse .

As progesterone promotes the growth of uterine fibroids, the blocking characteristic of ulipristal acetate can thereby be used to reduce the size of uterine fibroids. Ulipristal acetate has also shown efficacy with a significant reduction in uterine bleeding caused by uterine fibroids. The treatment of fibroids by ulipristal acetate should begin in the first week of a menstrual period .

Drugs or herbal products that induce enzymes, including CYP3A4, such as carbamazepine, phenytoin, rifampin, St. John's Wort, etc., may decrease the plasma concentrations of ulipristal acetate, and may decrease its effectiveness while CYP3A4 inhibitors such as itraconazole, ketoconazole, etc., may increase plasma concentrations of ulipristal acetate .

The half-life after oral intake is 32 h; it binds to plasma proteins for 97-99%, and it is metabolized by the citochrome P450 .


 
Our advantages:

1, High quality with competitive price:
1) Standard:BP/USP/EP/Enterprise standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.

2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment.Tracking number available
2) Secure and discreet shipment.Various transportation methods for your choice.
3) Customs pass rate ≥99%
4)  We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.

3,We have clients throughout the world.
 1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
3)  High quality,competitive price,fast delivery ,first-class service gain the trust and praise from the customers.