Chinese-Western combination treatment of infectious bursal disease and its complications

Infectious bursal disease (IBD) is an acute highly contagious disease in chickens that causes serious economic losses to the chicken farmer. The ability of the body suffering from infectious cystic disease to produce immune antibodies is diminished or disappeared, the resistance to the disease is reduced, virus diseases such as Newcastle disease and E. coli disease and mycoplasma diseases are easily complicated with chickens. If this happens, vaccination will not produce satisfactory immunity. force. In the veterinary clinic, general emergency injection of high-immunity yolk antibody, although there is a certain effect, but no effect on complications, so the complications can only take symptomatic treatment, so that the cost of treatment is relatively increased. In recent years, the author has tried to use the combination of Chinese and Western medicine for the treatment of IBD and its complications in several chicken farms in this city and received good results. The cure rate was as high as 93%. The treatment of IBD diseased chickens in one of the city's poultry farms is now reported as follows.

1 Incidence

In May 2005, some broiler farms in Heping Town of the city purchased 2,000 Hyland brown chicks, which suddenly developed on the 38th day of age. Eight dead on the day and 27 died on the second day. They quickly spread to the entire chicken population. The diseased chickens showed a lack of energy, shrinking their heads and tails, swelling and tearing of their eyes, fluffy feathers, limousine-like discharges, or dilute dung between yellow and white. According to the chief complaint, the chicks were immunized with a Newcastle disease IV strain vaccine once at 7 days of age and an IBD vaccine was used to immunize once a day at 14 days of age. The IBD vaccine was not used for the second immunization because of farmers being busy.

2 necropsy changes

The sinuses had yellow cheese-like material and mucus. There was a small amount of mucus in the trachea and the air bubbles were turbid. There was bleeding from the cysts of the bursal with yellow cheese-like material and mucus in the cyst. The muscles in the legs and chest were streaked. Other changes were not typical.

3 laboratory diagnosis

3.1 Sterilization The serum of 20 chickens was used for IBD agar diffusion test with standard IBD agarose antigen and positive serum. Eighteen positive reactions were performed, and the positive rate was 90%.

3.2 Aseptic manipulation One drop of each of 20 chicken bloods was taken on a clean glass plate. The standard CRD septic Mycoplasma agglutination antigen was used for whole blood plate agglutination reaction. Fifteen were positive and the positive rate was 75%.

3.3 Take the dead chicken liver to do ordinary culture, there are a small number of larger creamy colonies with white round smooth reaction, take the colony smear, Gram stain microscopy, as C +, grape-like arrangement of the cocci.

According to epidemiology, symptoms, necropsy changes, and laboratory diagnosis, the outbreak of IBD in this chicken farm was complicated by CRD and staphylococcal infection.

4 treatment

4.1 Chinese medicine formula: Pueraria, Radix isatidis, Coptis chinensis, Radix Scutellariae, Radix Astragali, Shuanghua, Pulsatilla, dandelion, Shandou root, and licorice each 200g. Usage and dosage: Calculate 1g of crude drug per day for each chicken, fry twice, take potable water, mix and feed freely, and supply enough sugar and salt water. Once a day for 4 days.
Fang Jie: Ge Genxin published muscle, thirst, spleen deficiency diarrhea; Coptis, astragalus, Radix, double flower heat purging detoxification, antibacterial anti-bacterial antibacterial; dandelion, Pulsatilla detoxification, cooling blood only, swelling swelling ; Huangqi, Shandou root qi sun, antibacterial anti-inflammatory, inhibit tumor growth, improve immunity; licorice reconcile various drugs.

4.2 Application of anti-inflammatory anti-Qianling Ling, each 10ml of water 5kg, drinking water twice a day, once every 5 days, the active ingredients of anti-bacterial anti-inflammatory, anti-virus.
Thirteen animals died on the 2nd day after treatment and 4 on the 3rd day. They basically recovered on the 6th day. The spirits of the chickens returned to normal and the cure rate was 97%.

5 Experience

At present, veterinary clinics tend to focus on a single western medicine, and western medicines have the disadvantages of toxic side effects, drug resistance, low utilization of active ingredients, residues, and high cost, while Chinese herbal medicines are inexpensive, non-toxic, no side effects, no residues, and no drug resistance. , And can Qingrexixue detoxification, antibacterial, anti-bacterial, cooling blood Zhiyu, swelling, Sanjie, Yang Qi, nourish the body, enhance the body resistance, so as to achieve a good therapeutic effect.

The author believes that the main cause of IBD disease in this chicken farm is inappropriate immunization procedures. Chicken bursal usually begins to develop after 10 days of age. Immunization before 10 days of age does not stimulate the production of antibodies in the bursal, even if it is low. According to the author's many years of experimental observation, the first immunity for infectious bursal disease in the region should be 14 days old, and the second exemption should be carried out at 28 days. The chicken farm was only once immunized, and the immune antibody produced was not strong, causing the disease on the chicken farm after the exogenous virus invaded the organism. For the treatment of complications, after several years of trial and treatment, the above-mentioned several types of comorbid treatment are better, as for other diseases to be further explored in the future.

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